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If you forget to take a dose of TOPROL-XLskip the dose you missed and take your next dose when you are meant to.

If clonidine and a beta blockersuch as metoprolol are coadministeredwithdraw the beta-blocker several days before the gradual withdrawal of clonidine because beta-blockers may exacerbate the rebound hypertension that can follow the withdrawal of clonidineIf replacing clonidine by betablocker therapydelay the introduction of beta-blockers for several days after clonidine administration has stoppedsee WARNINGS AND PRECAUTIONS

Ask your doctor if you have any questions about why TOPROL-XL has been prescribed for you.

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you can take lisinopril and metoprolol together but sometimes it may lower your blood pressure and can be the cause of slow heart rate, as a result you may feel fainting, weakness, irregular heartbeat, loss of glucose in blood and many others.