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; anticoagulants blood thinners such as warfarin coumadin ; antifungals such as griseofulvin fulvicin, grifulvin, grisactin , fluconazole diflucan , itraconazole sporanox , and ketoconazole nizoral ; atorvastatin lipitor ; clofibrate atromid-s ; cyclosporine neoral, sandimmune ; bosentan tracleer ; cimetidine tagamet ; danazol danocrine ; delavirdine rescriptor ; diltiazem cardizem, dilacor, tiazac ; fluoxetine prozac, sarafem, in symbyax ; hiv protease inhibitors such as indinavir crixivan and ritonavir norvir ; medications for seizures such as carbamazepine tegretol , felbamate felbatol , lamotrigine lamictal , oxcarbazepine trileptal , phenobarbital luminal, solfoton , phenytoin dilantin , primidone mysoline , and topiramate topamax ; modafinil provigil ; morphine kadian, ms contin, msir, others ; nefazodone; rifampin rimactane, in rifadin, in rifater ; oral steroids such as dexamethasone decadron, dexone , methylprednisolone medrol , prednisone deltasone , and prednisolone prelone ; temazepam restoril ; theophylline theobid, theo-dur ; thyroid medication such as levothyroxine levothroid, levoxyl, synthroid ; verapamil calan, covera, isoptin, verelan ; vitamin c; and zafirlukast accolate .

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in vivo, the plasma levels of phenytoin increased by up to 40 when trileptal was given at doses above 1200 mg day.

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consult with your doctor if you become pregnant while taking trileptal.

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the increase of phenobarbital level, however, is small 15 when given with trileptal.


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