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In patients with chronic renal impairmentwhose creatinine clearance ranged from 9-55 ml/minthe disposition of a single dose of 14 C-finasteride was not different from that in healthy volunteersProtein binding also did not differ in patients with renal impairmentA portion of the metabolites which normally is excreted renally was excreted in the faecesIt therefore appears that faecal excretion increases commensurate to the decrease in urinary excretion of metabolitesDosage adjustment in non-dialysed patients with renal impairment is not necessary.

Postmarketing reportsPruritusurticariaangioedemaincluding swelling of the lipstonguethroatand faceRef]

In patients with BPHPROSCAR has no effect on circulating levels of cortisolprolactinthyroidstimulating hormoneor thyroxineNo clinically meaningful effect was observed on the plasma lipid profilei.etotal cholesterollow density lipoproteinshigh density lipoproteins and triglyceridesor bone mineral density.

This document does not contain all possible interactionsThereforebefore using this producttell your doctor or pharmacist of all the products you useKeep a list of all your medications with youand share the list with your doctor and pharmacist.

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