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Acute and chronic rheumatoid arthritisChronic discoid or systemic lupus erythematosus.

Other medical conditionsIf you have stomachnervebloodor skin disorderstalk to your doctor about how this medication may affect your medical conditionhow your medical condition may affect the dosing and effectiveness of this medicationand whether any special monitoring is needed.

The methods recommended for early diagnosis ofchloroquine retinopathyconsist of1funduscopic examination of the macula for fine pigmentary disturbances or loss of the foveal reflex and2examination of the central visual field with a small red test object for pericentral or paracentral scotoma or determination of retinal thresholds to redAny unexplained visual symptomssuch as light flashes or streaksshould also be regarded with suspicion as possible manifestations of retinopathy.

Use of PLAQUENIL in patients with psoriasis may precipitate a severe attack of psoriasisWhen used in patients with porphyria the condition may be exacerbatedThe preparation should not be used in these conditions unless in the judgment of the physician the benefit to the patient outweighs the possible hazard.

Suicidal behavior has been reported in very rare cases in patients treated with hydroxychloroquine.

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there are a number of other much less important side effects of plaquenil, including changes in the cornea and changes in the eyelids.