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Talk to the doctor about the risks and benefits of treatmentespecially when used in teenagers

Patients may develop severe sedationcomaand or delirium after an injection of extended release olanzapinePatients must be examined for 3 hours after receiving an injection.

Olanzapine may be used as part of a combination therapyThis means you may need to take it with other medicationssuch as lithiumvalproateor fluoxetine.

There may be an increased risk of elevated blood sugar levels and diabetes with olanzapine as well as the other antipsychotic medications in its classPatients should be tested during treatment for elevated blood sugarAdditionallypersons with risk factors for diabetesincluding obesity or a family history of diabetesshould have their fasting levels of blood sugar tested before starting treatment and periodically throughout treatment to detect the onset of diabetesAny patient developing symptoms that suggest diabetes during treatment should be tested for diabetes.

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5 mg day on a once daily schedule, the two highest olanzapine dose groups actual mean doses of 12 and 16 mg day, respectively were superior to placebo on bprs total score, bprs psychosis cluster, and cgi severity score; the highest olanzapine dose group was superior to placebo on the sans.