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Patients who are on immunosuppressant doses of corticosteroids should be warned to avoid exposure to chicken pox or measles andif exposedto obtain medical advice.

The lowest possible dose of corticosteroid should be used to control the condition being treatedA gradual reduction in dosage should be made when possible.

The use of Florinef AcetateFludrocortisone Acetate Tablets USPin patients with active tuberculosis should be restricted to those cases of fulminating or disseminated tuberculosis in which the corticosteroid is used for the management of the disease in conjunction with an appropriate antituberculous regimenIf corticosteroids are indicated in patients with latent tuberculosis or tuberculin reactivityclose observation is necessary since reactivation of the disease may occurDuring prolonged corticosteroid therapy these patients should receive chemoprophylaxis.

Corticosteroids are contraindicated in patients with systemic fungal infections and in those with a history of possible or known hypersensitivity to these agents.

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