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Check the labels on all your medicinessuch as allergycough-and-cold productsdiet pillsbecause they may contain dextromethorphandecongestantsor stimulantsAsk your pharmacist about the safe use of those products.

No pharmacokinetic information is available on selegiline or its metabolites in hepatically impaired subjects.

When selegiline is used at its recommended doseit selectively inhibits MAO-BThe combined use of the SSRIfluoxetine and Eldeprylshould only be used under clinical supervision.

The decision to prescribe selegiline should take into consideration that the MAO system of enzymes is complex and incompletely understood and there is only a limited amount of carefully documented clinical experience with selegilineConsequentlythe full spectrum of possible responses to selegiline may not have been observed in pre-marketing evaluation of the drugIt is advisablethereforeto observe patients closely for atypical responses.

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