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In patients receiving diuretics and an ace inhibitor, or diuretics alone, the withdrawal of digoxin has been shown to result in clinical deterioration.

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drug interactions this medicine may interact with the following medications cholinesterase inhibitors; conivaptan; fluoxetine; neuromuscular blockers; parasympathomimetics; paroxetine; amantadine; amiodarone; amoxapine; antiretroviral protease inhibitors; antimusca- rinics; aprepitant, fosaprepitant; barbiturates; cimetidine; clarithromycin; clozapine; cyclobenzaprine; delavirdine; digoxin; disopyramide; efavirenz; erythromycin; flu- conazole; fluvoxamine; general anesthetics; imatinib, sti-571; itraconazole; ketocon- azole; local anesthetics; maprotiline; nefazodone; nilotinib; olanzapine; orphenadrine; phenothiazines; sedating h-1 blockers; st.

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