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This study demonstrated that, after 10 days of repeated oral administration followed by 7 days of intravenous administration, the oral and intravenous dosage forms of protonix 40 mg are similar in their ability to suppress mao and bao in patients with gerd and a history of erosive esophagitis see table 3 .

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Immune System Disordersanaphylaxisincluding anaphylactic shocksystemic lupus erythematosus.

Hypomagnesemiasymptomatic and asymptomatichas been reported rarely in patients treated with PPIs for at least three monthsand in most cases after a year of therapySerious adverse events include tetanyarrhythmiasand seizuresIn most patientstreatment of hypomagnesemia required magnesium replacement and discontinuation of the PPI.

Skin and Subcutaneous Tissue Disorderssevere dermatologic reactionssome fatalincluding erythema multiformeStevens-Johnson syndrometoxic epidermal necrolysisTENangioedemaQuincke’s edemaand cutaneous lupus erythematosus.

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