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Lamictal is used either alone or in combination with other medications to treat epileptic seizures in adults and children.

It is important to remember thisEven if you have been without bipolar symptoms for several monthsdo not stop taking your medicationsYour doctor may lower your dosesbut discontinuation of medications will put you at risk for recurrence of bipolar symptoms.

The elimination half-life and apparent clearance of lamotrigine following oral administration of LAMICTAL to adult subjects with epilepsy and healthy volunteers is summarized in Table 14Half-life and apparent oral clearance vary depending on concomitant AEDs.

Overdoses involving quantities up to 15 g have been reported for LAMICTALsome of which have been fatalOverdose has resulted in ataxianystagmusseizuresincluding tonic-clonic seizuresdecreased level of consciousnesscomaand intraventricular conduction delay.

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the effectiveness of monotherapy with lamictal was established in a multicenter, double-blind clinical trial enrolling 156 adult outpatients with partial-onset seizures.