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The safety and efficacy of NASONEX Nasal Spray has not been studied for use in the treatment of unilateral polypspolyps associated with cystic fibrosisor polyps that completely obstruct the nasal cavities.

Systemic effects of nasal corticosteroids may occurparticularly at high doses prescribed for prolonged periodsThese effects are much less likely to occur than with oral corticosteroids and may vary in individual patients and between different corticosteroid preparationsPotential systemic effects may include Cushing’s syndromeCushingoid featuresadrenal suppressiongrowth retardation in children and adolescentscataractglaucoma and more rarelya range of psychological or behavioural effects including psychomotor hyperactivitysleep disordersanxietydepression or aggressionparticularly in children

Although NASONEX Nasal Spray will control the nasal symptoms in most patientsthe concomitant use of appropriate additional therapy may provide additional relief of other symptomsparticularly ocular symptoms.

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